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In vitro bioassays for androgens and their diagnostic applications -- Roy et al. 14 (1): 73 -- Human Reproduction Update

The Author 2007. Published by Oxford University Press on behalf of the European Kingdom of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions oxfordjournals.org In vitro bioassays for androgens and their diagnostic applications P. Roy 1, M. Alevizaki 2, 3 and I.


Huhtaniemi 4, 5 1 Molecular Endocrinology Laboratory, Branch of Biotechnology, Indian Faculty of Technology Roorkee, Roorkee 247 667, Uttaranchal, India 2 Endocrinology and Metabolism Unit, Evgenidion Infirmary 3 Department of Medical Therapeutics, Alexandra Hospital, Athens University College of Medicine, 80, Vassilios Sofias Avenue, 11528 Athens, Greece 4 Department of Reproductive Biology, Imperial School London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK 5 Packages address.


One alternative to augment the clinical relevance of androgen measurements is if by the recently developed in vitro bioassays of complete androgen bioactivity in serum. These assays are not all the more ready for routine laboratory diagnostics, nevertheless they afford a brave thing for clinical evaluation in disturbances of androgen production.


Another manipulate of these assays is the screening for androgenic and antiandrogenic duration in chemical compounds, environmental samples and when suspecting androgen abuse. The destination of this article is to introduce the in fashion problems of androgen measurement by immunoassays, to exemplify the story in vitro bioassay techniques and to procession the contemporary counsel on their apply in clinical research.