In vitro bioassays for androgens and their diagnostic applications -- Roy et al. 14 (1): 73 -- Human Reproduction Update
The Author 2007. Published by Oxford University Press on behalf of the European Nation of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions oxfordjournals.org In vitro bioassays for androgens and their diagnostic applications P. Roy 1, M. Alevizaki 2, 3 and I.
Huhtaniemi 4, 5 1 Molecular Endocrinology Laboratory, Branch of Biotechnology, Indian Institution of Technology Roorkee, Roorkee 247 667, Uttaranchal, India 2 Endocrinology and Metabolism Unit, Evgenidion Infirmary 3 Department of Medical Therapeutics, Alexandra Hospital, Athens University Faculty of Medicine, 80, Vassilios Sofias Avenue, 11528 Athens, Greece 4 Department of Reproductive Biology, Imperial School London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK 5 Mail address.
One alternative to develop the clinical relevance of androgen measurements is if by the recently developed in vitro bioassays of complete androgen bioactivity in serum. These assays are not still ready for routine laboratory diagnostics, on the contrary they contribute a acceptable item for clinical test in disturbances of androgen production. Another operate of these assays is the screening for androgenic and antiandrogenic exertion in chemical compounds, environmental samples and when suspecting androgen abuse.
The location of this article is to introduce the ongoing problems of androgen measurement by immunoassays, to delineate the chronicle in vitro bioassay techniques and to check the in fashion earful on their practice in clinical research.
