In vitro bioassays for androgens and their diagnostic applications -- Roy et al. 14 (1): 73 -- Human Reproduction Update
The Author 2007. Published by Oxford University Press on behalf of the European State of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions oxfordjournals.org In vitro bioassays for androgens and their diagnostic applications P. Roy 1, M. Alevizaki 2, 3 and I.
Huhtaniemi 4, 5 1 Molecular Endocrinology Laboratory, Branch of Biotechnology, Indian Academy of Technology Roorkee, Roorkee 247 667, Uttaranchal, India 2 Endocrinology and Metabolism Unit, Evgenidion Infirmary 3 Department of Medical Therapeutics, Alexandra Hospital, Athens University Institute of Medicine, 80, Vassilios Sofias Avenue, 11528 Athens, Greece 4 Department of Reproductive Biology, Imperial Institution London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK 5 Letter address.
One alternative to convalesce the clinical relevance of androgen measurements is if by the recently developed in vitro bioassays of complete androgen bioactivity in serum.
These assays are not still ready for routine laboratory diagnostics, on the other hand they dispense a favorable item for clinical trial in disturbances of androgen production. Another practice of these assays is the screening for androgenic and antiandrogenic life in chemical compounds, environmental samples and when suspecting androgen abuse.
The desire of this article is to introduce the happening problems of androgen measurement by immunoassays, to chronicle the version in vitro bioassay techniques and to check the in fashion clue on their exercise in clinical research.
