Heterozygosity for the Classical Galactosemia Mutation Does Not Affect Ovarian Reserve and Menopausal Age -- Knauff et al. 14 (8): 780 -- Reproductive Sciences
Reproductive Sciences, Vol. 14, No. H. Knauff, MD Branch of Reproduction and Gynecology, University Medical Center, Utrecht,The Netherlands, knauff at gmail.com Renate Richardus, MD Department of Pediatrics, Academic Medical Center, University of Amsterdam, The Netherlands Marinus J. Eijkemans, PhD Department of Habitual Health, Erasmus Medical Center, Rotterdam, The Netherlands Direct J. Broekmans, MD, PhD Department of Reproduction and Gynecology, University Medical Center, Utrecht,The Netherlands Open J.
Jong, PhD Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands Bart C. J. M. Fauser, MD, PhD Department of Reproduction and Gynecology, University Medical Center, Utrecht,The Netherlands Annet M.
Earlier trial has suggested an society between heterozygosity for GALT mutations and early menopause. This recite evaluates the denouement of carriership for classical galactosemia on ovarian reserve and menopausal age. Proven female carriers of classical galactosemia were recruited via the Dutch Galactosemia Society. All 58 participants underwent a structured interview regarding fertility, smoking status, and menopause.
The selfish day at menopause in GALT carriers was 49.7 years, which is not deviating from the miserly date at menopause in the habitual population in the Netherlands. The authors conclude that there is no evidence that GALT mutation carriership affects ovarian reserve or menopausal age.
